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PDGF-BB is a factor with strong chemotactic and mitogenic action on the pericytes while the FGF2 induces proliferation mostly on the endothelium

Moreover, hydrochlorothiazide have been shown to diminish insulin secretion from islets of obese mice by reducing Ca 2+ influx rather than altering [Cl ] i , K + or Cl fluxes (Sandstrom et al., 1993)

Treatment will depend largely on the cause of a deficiency

So, additional investigation is necessary to link these potential associations to konzo pathogenesis, particularly in relation to time of disease onset, as such markers may only be present during early phases of konzo onset when inflammation or neural damage is likely highest

Moreover, BP polysaccharides from corn enhance the activity of immunocytes in the body such as lymph nodes, spleen, thymus gland, and bone while strengthening immunity of the body against pathogenic microbes (22)