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There are two main types, acute pancreatitis and chronic pancreatitis Acute pancreatitis: Sudden, severe pain in centre of stomach Stomach swelling Nausea/vomiting Diarrhoea Indigestion High Temperature- above 37.5 C Jaundice - yellowing of eyes & skin Chronic pancreatitis Frequent episodes of stomach pain Recurring Indigestion Recurring nausea & vomiting Weight loss Jaundice Loss of appetite Needing to urinate often* Fatigue* Being thirsty* * Symptoms of new onset diabetes Chronic pancreatitis is linked to an increased risk of pancreatic cancer but the reasons why this is the case are still unclear and research is still ongoing

2.4 Pretreatment Adolescent (P2831) and adult (P8689) rats received a drug pretreatment for 4 consecutive days (32)

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