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Therefore, a promising strategy that combines immune checkpoint inhibitors (ICIs) with ferroptosis inducers that activate the PKCII-ACSL4 pathway can be introduced in cancer therapy

Microbiotagutbrain axis in the context of bipolar disorder pathophysiology To simplify, the pathophysiological mechanisms by which the MGB axis seems to influence the development of BD are (1) through modulating the enteric and central nervous system (CNS), with a focus on its immunomodulatory actions while influencing the intestinal, systemic and brain inflammation

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Meanwhile, DNase Il3 and DNase I may prevent disseminated intravascular coagulation (DIC) by degrading NETs (201)

MIT Press, Cambridge Marotta R, Risoleo MC, Messina G, Parisi L, Carotenuto M, Vetri L, Roccella M (2020) The neurochemistry of autism