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Additionally, low level (10 M) H 2 O 2 treatment induced JNK-mediated FOXO3a translocation and activation to promote AKT-mediated stem cell proliferation, which when transplanted, increased re-epithelialisation and angiogenesis in wounded mice 147

Research has demonstrated that transcription factors, including SNAI1, TWIST1, and ZEB1, can advance EMT and promote drug resistance in tumor cells [97]

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