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Studies indicate that the number of infiltrating T cells peaks between days 3 and 7 post-stroke, thereby exacerbating brain injury and neuroinflammation ( Notably, RIPreC and RIPostC exert distinct immunomodulatory effects on different T cell subsets, reflecting the time-dependent nature of their application

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Kim, S.-K., Yoon, Y.-D., Park, Y.-S., Seo, J

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This conversion is a critical step in the folate cycle [Figure 1], with 5-methyl-THF subsequently serving as a substrate for the methylation of homocysteine (Hcy) to methionine (Met)