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Therefore, DPP-IV inhibitors counteract this process by binding to the enzymes active site, altering its catalytic activity, and preventing the breakdown of incretins

specifically, the fleeting existence of radical species and the rapid rate at which redox cycling can generate ROS, causing oxidative stress 5,7,28

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doi: 10.3390/metabo12111064 35

CoanLJWilliamsBMKrishna AdithyaVUpadhyayaSAlkafriACzannerSet al

Previous in vitro studies demonstrated that reduced GSH levels in tumor cells promoted cell death, while elevated levels inhibited cell death [18]