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Funding Research was funded by UC Berkeley startup funds and the Winkler Family Foundation

This review highlights the role of metabolomics in characterising metabolic alterations in CKD, including disruptions in amino acid metabolism, oxidative stress pathways, and the accumulation of uremic toxins

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Using CE-TOFMSbased metabolomics of rat serum after intratracheal instillation, we compared polyacrylic acid (A45, a fibrogenic polymer) with polyethylene glycol (PEG, a biocompatible negative control)