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Description

Supplementation with exogenous SP was able to reverse intestinal barrier disruption, and SP dose-dependently protected against intestinal inflammatory damage

doi: 10.1016/j.crmeth.2021.100153

This redox guardian operates via three synergistic mechanisms: primarily by enhancing GSH synthesis under oxidative stress, secondly through maintaining GSH availability to preserve GPX4 activity (Chen et al., 2022), and finally via ferritin stabilization to suppress iron-driven lipid peroxidation