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Nonetheless, an impaired relationship between neurons and astrocytes might be a common component

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To date, the most promising clinical trial focuses on the progressive muscle disease mitochondrial myopathy 244

[2] [11] As of 2026, retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), and it remains an experimental compound available only within authorised clinical trial settings