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The EphA subgroup includes nine members (EphA1-A8 and A10) and the EphB subgroup five members (EphB1-B4, B6)

ROS act as upstream regulators of degradative enzymes such as matrix metalloproteinases (MMP-1, MMP-3, and MMP-13), which contribute to the breakdown of type I collagen, a key structural component of the tendon ECM