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The inactivation of Dnmt3a and Dnmt3b during early embryonic development hindered de novo methylation (Feng et al., 2010)

However, in pregnancies with high blood sugar levels (such as those with GDM), the placenta's development can be affected, leading to various complications such as increased oxidative stress, fetal thrombosis, maternal vascular malperfusion, and an imbalance in vasoactive molecules

Further research is needed to determine whether eating foods rich in vitamin B12 or taking supplements can improve headaches

Blaj LA, Cucu AI, Tamba BI, Turliuc MD

Throughout the reproductive lifespan, women typically undergo over 400 cycles of endometrial regeneration, differentiation, and shedding (Lv et al., 2018)