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Proceed Ntl Acad Sci USA 115(27):E6099-100 Devkota S, Joseph RE, Boyken SE, Fulton DB, Andreotti AH (2017) An Autoinhibitory Role for the Pleckstrin Homology Domain of Interleukin-2-Inducible Tyrosine Kinase and Its Interplay with Canonical Phospholipid Recognition