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It also demonstrates antioxidant activity via superoxide dismutase upregulation

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What the clinical trials actually found Six randomized, double-blind, placebo-controlled trials involving over 900 participants have evaluated AOD 9604 in humans

This suggests that when the subcutaneous depot is formed, the slow release of buprenorphine from the depot becomes the rate limiting factor and any difference in adipose tissue composition has no or limited impact on buprenorphine absorption