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doi:10.2174/138161207780618920

Melatonin receptors are widely distributed throughout the brain, encompassing various regions involved in circadian regulation, sleep-wake cycles, mood modulation and neuroendocrine function

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Proponents say they are useful in helping smokers quit their habit, but public health advocates are concerned that they also carry a risk of addiction with uncertain risks

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If you a first-time nicotine user, you can start with a lower strength, or nicotine-free option, and then work up or down depending on which strength you end up preferring