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Radiat Oncol J 36:254264

Phase l dose escalation and expansion of ziftomenib in combination with quizartinib in AML

Our protocol for inducing global hypoxia in neonatal mice was based on the procedure described previously 55,56

Approach Community research planning Duration 8-16 weeks Review Point Every 4 weeks Notes Common research-planning structure with optional review points

Catalytic efficiencies and reciprocal Dalziel coefficients of Y110A in the HEDS assay were decreased to 36% of the wild-type enzyme (Supplementary Fig