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TB-500 nasal spray is an intranasal supply form of TB-500, a synthetic peptide derived from the highly conserved C-terminal region of Thymosin Beta-4 (T4), the 43-amino acid actin-sequestering protein expressed in virtually all mammalian nucleated cells

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Its structure incorporates specific amino acid substitutions to enhance solubility and prevent fibril formation, along with the addition of a C18 fatty diacid moiety via a linker

A lower Ce 3+ /Ce 4+ ratio has been reported to support cytochrome-like activity, and a higher Ce 3+ /Ce 4+ ratio is consistent with enhanced SOD-like activity (Singh et al

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